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While the Rotterdam criteria are widely used for PCOS diagnosis, their development was based on expert meetings rather than evidence-based treatment guidance, and they do not incorporate clinical manifestations that might be essential to distinguish phenotypes, such as metabolic parameters

Kim J, Kundu M, Viollet B, Guan KL

Creatine Creatine is a substance produced naturally in the body to help generate ATP in cells which is used as energy

It is specifically designed to provide a range of potential benefits to the human body

In PCOS, the convergence of hyperandrogenism-driven adipokine dysregulation, insulin resistance, and macrophage infiltration sets up a permissive environment for neutrophil activation [22, 23]

This sudden spike can overwhelm the body's ability to process alcohol, raising the risk of overdose