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In type A intercalated cells the basolateral membrane localized Cl /HCO 3 exchanger is AE1 (encoded by the SLC4A1 gene) and this transporter mediates HCO 3 reabsorption from the blood

Immunol Cell Biol (2011) 89(1):13042

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Conclusion: Cinchonine, a potential oral small-molecule GLP-1R agonist, could reduce blood glucose and ameliorate NASH, providing a strategy for developing small-molecule GLP-1R agonists

M.Soussi-YanicostasN