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Direct cortisol-lowering is not semaglutide's primary mechanism, but clinical observations suggest GLP-1 activation may normalize cortisol's diurnal rhythm and reduce stress-induced cortisol spikes

[DOI] [PubMed] [Google Scholar] 73.Tao SC, Yuan T, Zhang YL, Yin WJ, Guo SC, Zhang CQ

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A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice

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falciparum 3D7-infected erythrocytes (ring stage 610 h post invasion) were incubated with 4IC 50 of MB