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289 A phase 3 trial (NCT06128629) is currently underway, enrolling 765 patients with ATTR-CM to evaluate the long-term efficacy and safety of NTLA-2001

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5-Amino-1MQ represents a breakthrough NNMT inhibitora small-molecule compound that potently suppresses NNMT activity, allowing NAD+ to accumulate and activate metabolic health pathways

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