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Immune and inflammatory factors Immune and inflammatory factors are thought to play key roles in the pathogenesis of infertility in patients with endometriosis, by reducing gamete quality and rates of gamete transport and implantation, and by increasing rates of pregnancy loss

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Wang et al., 2011

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Since we do not have a good way of predicting which dogs with mild disease will progress to clinical signs, it becomes difficult to decide whether or not to recommend pimobendan for some patients