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In a normal neuromuscular junction, AChR in the membrane of signal-receiving motor neurons binds to the released neurotransmitter acetylcholine and causes a depolarization of the membrane

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Their use in this context represents off-label prescribing, which requires careful clinical justification and informed patient consent

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Leisman did not respond to requests for an interview, but he told The Transmitter in 2023 that the participants in the 2020 study came from a client database for Brain Balance Achievement Centers, a Chicago-based franchise

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