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Adding BOTH glucagon AND GIP (retatrutide) brings it to 28.3% about 11 percentage points of additional benefit

However, AOD-9604 is listed on the WADA Prohibited List and must not be used by athletes

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Some patients reported nausea, leading Novo to reduce the dose, but efficacy was disappointing

For further studies we suggest to involve complexes 1 and 3 , possessing strongly bound ligands, as suitable model complexes both biologically relevant oxidation states +II and +III, with good solubility in water and biological media