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Briefly, the process proceeds with the mRNA synthesis of seleno-GPxs by transcription factors followed by in situ synthesis of Sec on a specific set of tRNA designated as tRNA [ser]Sec and its incorporation into the peptide sequence against the termination codon UGA within ribosomal machinery (Fig

This helps prevent early ageing and skin damage

Alternatively, impaired intestinal barrier function allows microbial translocation

doi: 10.3389/fimmu.2025.1593691 290 LiWWangXChenYDingYLingXYuanBet al