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Supply and Distribution Constraints This sudden increased demand for GLP-1s eventually led to supply shortages starting in March 2022, with a key contributing factor being the underlying difficulty of manufacturing peptide-based drugs

Individuals with certain health conditions, such as kidney disease, heart conditions, or high blood pressure, should consult a healthcare provider before treatment

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Clinical trials show Wegovy achieves average weight loss of 15-22% of body weight over 68 weeks in people who maintain lifestyle changes