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*Correspondence: Shokrollah Elahi, [email protected] ORCID: Shokrollah Elahi, orcid.org/0000-0002-7215-2009 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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The UPR is mostly initiated for the restoration of ER function, although it can perform the role of a binary switch between cell death and survival

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