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Ball GD, Hamade H, Gottlieb AB, Kirby B, Callis Duffin K

improves the export and burning of fat from the liver helps in the synthesis of carnitine helps in brain development and memory and supports the maintenance of a healthy nervous system

MW ~1,419 Da) studied for cytoprotection, VEGF/EGF pathway modulation, and tissue repair in preclinical models

Targeted apoptosis of macrophages and osteoclasts in arthritic joints is effective against advanced inflammatory arthritis

The approval was backed by the Phase II open-label AGAVE-201 trial, where treatment with a 0.3-mg/kg dose of Niktimvo elicited an overall response rate of 75%, with a median time to response of 1.5 months

Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer