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This graduated approach minimizes side effects while progressively increasing therapeutic benefit

The role of GLP1 receptor agonists in adult-onset type 1 diabetes mellitus

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Although no specific definition is used in the literature for clinically significant WR, it can be defined as progressive weight gain after a successful initial weight loss [1]

Fortunately, proven strategies including gradual dose titration, dietary modifications, eating smaller meals, and staying well-hydrated can significantly reduce this side effect

Some people barely notice anything at the starting dose, then get hit with significant sulfur burps when they move to the next dose level