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These findings make it scientifically interesting, but they remain preclinical and cannot establish effectiveness in people

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Neuroprotection by anti-neuroinflammation Microglia are resident phagocytes of the innate immune system in the CNS and are the first responders to neuroinflammation or damage to maintain brain homeostasis [182]

Together, they demonstrate the clinical viability of the GLP-1/glucagon dual-agonist concept and suggest that this mechanism class will be a significant addition to the metabolic disease treatment landscape alongside tirzepatide and emerging triple agonists like retatrutide

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