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Hair loss is one of the most emotionally distressing side effects reported by people taking semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), and the concern is backed by real data

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Factors influencing individual results include: Baseline metabolic health and insulin resistance Adherence to dietary and physical activity recommendations Genetic predisposition to weight loss Concurrent medications that may affect weight Psychological factors and eating behaviours Patients should maintain realistic expectations: whilst significant abdominal fat reduction is achievable, GLP-1 therapy will not produce a flat stomach or eliminate all belly fat, particularly in those with substantial weight to lose

Huang and K.-L

Gen Comp Endocrinol (2018) 260:517