Ongoing research is exploring its potential applications in conditions such as non-alcoholic fatty liver disease (NAFLD), cardiovascular risk reduction, and even as an adjunct therapy for weight loss in non-diabetic individuals
Hassan A, Tsuda Y, Asai A, et al
Compounded medications (offered by TrimRx, MEDVi, Eden, and Willow) use the same active ingredients as brand-name drugs but are not FDA-approved finished products
It does, however, establish that less than maximum dosing can preserve some of the benefit, while also demonstrating a dose-response more efficacy with higher dose
This is the same mechanism used in semaglutide and other long-acting GLP-1 drugs
For this reason, eligibility decisions in enhanced athletes cannot currently rely on PED-specific validated cut-offs, but must instead be guided by existing sports cardiology principles, individualized risk stratification, and longitudinal reassessment