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In the original study, FOXO4-DRI showed 11.73-fold selectivity for senescent versus non-senescent human fibroblasts

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Such studies may help clarify how structural organization emerges from the interaction of cellular, molecular, and extracellular factors across multiple tissue types

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In diabetic patients, the progressive retinal damage associated with hyperglycemia and other diabetes-related factors is linked to the abnormal wound healing pathways in the eye [7]

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