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As described in the results section, the animals included in the experimental design, including the non-androgenized controls, were fed a high-fat diet with 58% kcal from fat, 25.5% from carbohydrates, and 16.4% from proteins (Research Diets, D12331)

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Glucagon-like peptide-1 receptor agonists (semaglutide and tirzepatide) are a class of medications approved by the U.S

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Most experience the most intense tiredness during the initial 4 to 8 weeks, but it tends to recede with time, cleaner eating, and proper hydration

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Wysham C, Blevins T, Arakaki R, et al

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doi: 10.1111/obr.12603

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