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He called the four months after going off medication a roulette wheel of binges, diets, exercise regimens and mental and emotional battles with myself over will power, self-image and motivation. Olson said he gained back five pounds within two months, but was eventually able to lose it by imposing a strict regime: 12 hours of exercise a week and an extremely high-protein diet

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Real-world cases and clinical guidance show that such measures make a big difference in comfort levels for IBS patients on GLP-1 therapy

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They cited Pyo et al