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The primary carnitine shuttle system in mitochondria comprises two enzymes (carnitine palmitoyl transferase 1 [CPT1] and CPT2) and an inner mitochondrial membrane transporter, carnitine/acylcarnitine carrier (CAC), also known as solute carrier 25 member 20 (SLC25A20)

Axitinib Axitinib is a small-molecule tyrosine kinase (TK) inhibitor targeting vascular endothelial growth factor receptors (VEGFRs)

However, due to excess calorie intake or insulin resistance , this process is disrupted

Additionally, GLP-1 agonists are not recommended for those who are pregnant, planning to become pregnant, or breastfeeding

Adams et al, 2020)