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It depends entirely on the concentration

These medications are often used for weight loss in people without diabetes

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Researchers became interested when early trials demonstrated unprecedented efficacy in metabolic controlwith some studies showing nearly 30% of subjects achieving normoglycemia and over 20% average weight losseffects that suggested the dual incretin approach might unlock mechanisms beyond what single-target agonists could achieve

Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes

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