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Participants who stopped semaglutide at week 68 (orange) regained most of their lost weight within a year net loss shrank from 17.3% to 5.6% by week 120

And it causes significant weight loss at 36 weeks across 3 different doses

This pattern holds true across many phased treatment types, not only this one compound, and reflects how gradual dose adjustment is generally approached in clinical practice

Apr 2, 2026 What if the real reason your GLP-1 results have stalled is not your dose, your timing, or your genetics