Mechanistically, the role of KHK in alcohol preference is most likely due to the role of fructose metabolism in the activity levels of aldehyde dehydrogenase (ALDH), the mitochondrial enzyme that metabolizes the toxic intermediate in ethanol metabolism, acetaldehyde
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Risks to Patients with Serious Cardiac Disease Advise patients that there are potential risks to patients with serious cardiac disease, including sudden death, with VYVANSE use
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