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Remarkably, GLP-1Rs are highly expressed in various tissues, including pancreatic cells, brain, endothelium, lung, GIT, kidneys, and immune cells (Baggio and Drucker 2021)

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If constipation persists beyond two weeks, discuss stool softeners with your PlexusDx providerthey're safe alongside semaglutide and prevent complications

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This is reference research information, not a recommendation to self-administer