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In addition to the pancreas, accumulating evidence suggests the brain as another important GLP-1 responsive organ that can mediate GLP-1s anti-obesity actions (Figures 2EG)

71%) liver tumors than did wild-type mice exposed to a peroxisomal proliferator (Wy-14,643), suggesting carcinogenic response is a possible consequence of structural differences in human and mouse PPAR-(Morimura et al

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Preference for weekly dosing over daily regimens supports widespread adoption and market dominance