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Similar alterations in ghrelin signalling have also been reported in cachectic states, in which circulating ghrelin concentrations are frequently elevated despite persistent anorexia, weight loss, and depletion of fat mass [166]

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doi: 10.1002/biof.5520280101 41 MashimoMNishikawaMHiguchiKHiroseMWeiQHaqueAet al