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1422-P: The potential of semaglutide once-weekly in patients without Type 2 Diabetes with weight regain or insufficient weight loss after bariatric surgery

The approved update to the Summary of Product Characteristics (SmPC) for Wegovy is aimed at healthcare providers, including doctors and pharmacists

NO produced by nitric oxide synthase eNOS and nNOS, in the presence of GSH, can effectively modulate vessels and neuronal functions, regulating the blood flow according to the local calcium influx

As shown in Figure 6, treatment of HL7702 cells with 300 M H 2 O 2 for 12 h reduced the PPAR- mRNA and protein levels in HL7702 cells

This effect can help reduce the urge to snack or overeat, which is particularly beneficial for those struggling with weight management and impulse control