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Jul 2009;40(3):180-9

Ipamorelin This pentapeptide secretagogue is commonly selected to explore ligandreceptor engagement, cAMP/PKA and PLC/IP 3 /Ca 2+ readouts, and structureactivity relationships in cell systems

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Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation in the GPX1 knockout mice, in addition to structural abnormalities in cardiac mitochondria and myocytes, suggesting GPX1 may play an important role in protecting cardiac mitochondria from reoxygenation damage in vivo

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