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It lacks FDA approval of the specific final formulation, which is granted to Novo Nordisks finished drug product, not the molecule itself

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Small molecules simply cant make enough contact, which is why oral GLP-1 agonists were out of reach for decades

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Key (Fostered) Laboratory of the Health Commission of Guangxi Zhuang Autonomous Region (ZTJ2020005)

Its difficult to prescribe a less effective drug while knowing that theres something better out there, says Yasmin Mesquita, a medical student and researcher at the Federal University of Rio de Janeiro in Brazil