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Long-term hyperglycemia and acute blood glucose fluctuations induce oxidative stress, causing endothelial dysfunction in diabetic patients [50, 249]

So when a treatment plan helps lower systolic blood pressure, it may support better cardiometabolic health

Sometimes, however, a drugs dose can be so variable that the manufacturer provides a sufficient quantity in the single-use vial to accommodate a wide range of amounts

All in all, B12 shots are both safe and efficacious

Workup including liver biopsy and autoimmune markers did not identify instances of concern for autoimmune DILI in cases involving atorvastatin, simvastatin, and fluvastatin, there was no indication as to whether the cases involved predominantly hepatitic vs cholestatic liver injury

Thiel KW, et al