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Semaglutide, a GLP-1 receptor agonist, works by mimicking a hormone in the body that helps control blood sugar and appetite

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Future directions also include the development of new immunotherapy agents or combinations that improve the efficacy of immunotherapy in PCa, including the combination of ICIs with inhibitors that target myeloid-derived suppressor cells (MDSC), 578,579 cancer-associated fibroblasts (CAF), 580 hypoxia, 581 or other cancer immune response suppression factors such as KDM5B, PTPN2, SOCS1, ADAR1, MYC, and integrin v6

Rybelsus is the FDA-approved oral formulation, taken daily rather than weekly

It reflects long-term blood sugar control rather than a single moment