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This review seeks to highlight emerging evidence that suggests a growing benefit of GLP-1 RAs irrespective of T2DM status in coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF), and blood pressure

215,216 The GIP/GLP-1 receptor agonists have an additional agonism effect at the GIP receptor, resulting in increased insulin secretion in a glucose dependent manner and combined effects on appetite regulation and weight loss

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Clinical Evidence Linking GLP-1 Therapy to Migraine Improvement Although large-scale randomized controlled trials specifically designed to test semaglutide for migraine prevention remain limited, real-world clinical data and mechanistic studies paint a promising picture

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