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Obstet Gynecol

Diabetes (2016) 65:1196207

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Clinically, plasma malondialdehyde (MDA)a byproduct of lipid peroxidationserving as a biomarker of oxidative stress severity, with elevated levels correlating with accelerated lung function decline in COPD patients

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Our central hypothesis is that CR activates metabolic reprograming pathways in DM defined by cancer hallmarks (e.g., uncontrolled cell proliferation, tumor suppressors loss etc.), while suppressing immune system surveillance