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To understand the physiological effects of endogenous GIP receptor activation, the development of GIP receptor antagonists has been essential

demonstrated that the DPP4-inhibitor vildagliptin reduces lipid accumulation by inhibiting adipogenesis, without affecting lipolysis through NPY cleavage and subsequent NPY Y2 receptor activation (77)

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Declaration of patient consent The authors certify that they have obtained written informed consent from all the patients