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J Pharm Biomed Anal 209:114477

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Most published work on BPC-157 involves cell culture systems, isolated tissue models, chick chorioallantoic membrane assays, or standardized rodent models

The fusion peptide demonstrated sleep-promoting effects, influenced neurotransmitter levels (5-HT, glutamate, dopamine, melatonin), and confirmed that the Tat cell-penetrating sequence was the more effective BBB carrier of two tested candidates establishing DSIP as a validated active scaffold for BBB-crossing fusion peptide sleep research and supporting the development of next-generation DSIP-based neuromodulatory tools

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