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Selenium is an essential mineral that is found in significant amounts in brazil nuts

Environ Sci Pollut Res 28(33):4535345363 Jiang M, Zhang J (2002) Water stress-induced abscisic acid accumulation triggers the increased generation of reactive oxygen species and up-regulates the activities of antioxidant enzymes in maize leaves

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Less common but serious risks include pancreatitis, gallbladder disease (including gallstones), acute kidney injury (usually secondary to dehydration), and a possible increased risk of medullary thyroid carcinoma, which has been observed in rodent studies but not confirmed in humans

this can be familial and has a 50% recurrence risk when it is

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