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doi: 10.2147/DMSO.S425642 41 ChoiRHKarasawaTMezaCAMaschekJAManuelAMNikolovaLSet al

Degraded peptide may have lost its copper-binding capacity, creating a solution of free copper rather than beneficial GHK-CU complex

The GSTM1 polymorphism is associated with a decline in the expression of the protein, which is a risk factor