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Deep generative learning prediction of druggable chemicals provides rapid predictions of receptor binding compounds and antibiotics from database (Zhavoronkov et al., 2019
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It has been reported to inhibit sickle RBC adhesion to the endothelial cells and to reduce tumor necrosis factor-induced vasocclusion
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Mechanistic endpoints were recorded when available, including markers of inflammation, angiogenic activity, collagen organization, and bone remodeling