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[39] Moreover, we declined the applicant's request to remove the anterior and lateral approaches from the descriptor and, instead, stated that the anterior and lateral approaches should remain in the descriptor and clarified our intent that the descriptor address all potential surgical approaches

There would be a tremendous benefit, both at the individual level and the society-wide level, if there were a meaningful breakthrough that could stop cognitive decline. The goal of stopping cognitive decline is driving diversification in the types of drugs under development, several of which are disease-modifying small-molecule drugs and biologics

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Prior authorization requirements, step therapy protocols, and BMI thresholds create additional barriers