ABC News (2022)
[10] [4] Kidney-related symptoms such as markedly reduced urine output, dark scant urine, or swelling in the legs may indicate acute kidney injury from dehydration and require urgent evaluation
However, semaglutide and placebo had similar number of drinks per calendar day, and number of drinking days over the 9-week study period (line graph below)
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It plays a key role in glucose and appetite regulation by: Stimulating insulin release (glucose-dependent) Suppressing glucagon secretion Slowing gastric emptying Increasing satiety and reducing appetite In people with type 2 diabetes, this GLP-1 response is impaired leading to poor glycemic control