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Carolyn Bramante, who works in the weight management clinic at the University of Minnesota says she still uses metformin "quite often" for patients with a host of weight-related issues, including type 2 diabetes, pre-diabetes, and obesity, too

The clinical relevance of these results seems also highlighted by the evidence that for some outcomes the clinical benefit is consistent irrespective of the presence of type 2 diabetes [13], advanced age [13, 30], and the background cardiorenal disease [12, 15, 31]

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