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First GLP-1 agonist, semaglutide, was found to be very effective and entered the market ( N -terminus of proteins and peptides
Gross, B., Pawlak, M., Lefebvre, P
Your clinician will weigh it against labs, history, and goals
Payers will pay a premium for demonstrated superior efficacy in a hard clinical endpoint, meaningful reduction in administration burden (infusion center visits eliminated, injection frequency reduced), or meaningful safety improvement (reduced immunogenicity leading to fewer treatment failures over multi-year use)
Dosage adjustments may also be necessary if the patient has moderate or severe renal dysfunction
*Denominacin Comn Internacional (DCI)
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