10.1098/rsob.180138 Open Biol
[DOI] [PMC free article] [PubMed] [Google Scholar] Smeets K, Opdenakker K, Remans T, van Sanden S, van Belleghem F, Semane B, Horemans N, Guisez Y, Vangronsveld J, Cuypers A
Regular monitoring and dose titration minimize adverse effects
This decision should always be made with a healthcare provider.
Endocrine guidelines focus on diagnosing and treating true adult GH deficiency and emphasize structured evaluation and follow-up rather than optimizing GH in otherwise healthy people (Molitch et al., 2011)
Meta-analyses of resistance-trained populations show that creatine supplementation reduces lean-mass loss by approximately 0.51 kg when combined with consistent weightlifting and adequate protein intake