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The disorder is characterized by seven biochemically distinct alterations, all resulting in the increase in concentrations of homocystine and methionine in body fluids (Table 1)

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Recent reports have shown that GLP-1 receptor agonists such as liraglutide and semaglutide, which are currently approved for treating type 2 diabetes, decrease alcohol-seeking behaviors by inhibiting the mesolimbic reward system of the brain