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Abstract Acanthosis nigricans (AN) is characterized by dark, coarse and thickened skin with a velvety texture, being symmetrically distributed on the neck, the axillae, antecubital and popliteal fossae, and groin folds, histopathologically characterized by papillomatosis and hyperkeratosis of the skin

It works synergistically with incretin pathways to reduce food intake and enhance satiety signals, supporting studies on obesity management and energy balance

Chronic episodes lasting over 4 weeks may indicate inflammatory bowel disease, celiac disease, or medication side effects from antibiotics, NSAIDs, or diabetes drugs like metformin

Substantial data in the literature support the role of vitamin D deficiency in the development of chronic health problems

The study demonstrated that the co-administration of Cagrilintide and Semaglutide resulted in significant and dose-dependent weight loss that was greater than either monotherapy, laying the groundwork for further research

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