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Bennett-Guerrero E, Veldman TH, Doctor A, Telen MJ, Ortel TL, Reid TS, et al

Lutsenko S, Roy S, Tsvetkov P (2025) Mammalian copper homeostasis: physiological roles and molecular mechanisms

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Supporting methylation without addressing gut inflammation or nutrient imbalances can temporarily worsen symptoms

Vitamin C or L-ascorbic acid Using a vitamin C serum for melasma can be an effective part of your pregnancy skincare routine

If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy