Most patients report that diarrhea improves within 26 weeks as the body adapts to the medication
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Originally developed to treat type 2 diabetes, semaglutide works by mimicking a hormone called GLP-1 that targets areas of the brain involved in regulating appetite and food intake
United States Patent US9993430B2 Buckley ST, Bkdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rnne J, Madsen KG, Schele SG, Alanentalo T, Kirk RK, Pedersen BL, Skyggebjerg RB, Benie AJ, Strauss HM, Wahlund PO, Bjerregaard S, Farkas E, Fekete C, Sndergaard FL, Borregaard J, Hartoft-Nielsen ML, Knudsen LB (2018) Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist
Because both substances affect blood sugar and digestion, taking them at the same time can lead to additive effects. This means the two substances might stack their impact, making the effects much stronger than if you took either one alone
Stopping abruptly can cause fluctuations in blood glucose or appetite, depending on the reason for therapy
