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Selenium is a key part of antioxidant enzyme glutathione peroxidase

Specific peptides can be immunomodulatory

Some doctors prescribe a vitamin B12 shot regularly, which they can give you in the office or teach you to do it yourself at home

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Beyond its association with vascular risk and cognitive decline (which we cover in our B12 for memory and brain health guide), elevated homocysteine has been linked to neuroinflammation and oxidative stress in brain tissue both of which are implicated in mood disorders

Long-term safety beyond 12 weeks has not been formally studied in large populations