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Dulaglutide when used as treatment for type 2 diabetes was also shown to improve liver function, especially gamma-glutamyl transpeptidase values over time without significant reductions in ALT or aspartate aminotransferase levels[25]
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Semaglutides cardiovascular benefit data (the SELECT trial, 2023) remains a distinct advantage for high-risk patients, and this consideration may guide some providers to recommend semaglutide even for patients currently on tirzepatide
OATP1B1 exhibits the broadest substrate specificity, while other subtypes display more selective affinities
