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The acute decrease in UMP/UDP/UTP levels that resolves despite continued TS inhibition supports the hypothesis that an increase in nucleotide salvage might be linked to our observed mitochondrial phenotypes

Occasional headache or lightheadedness during initial use

Common side effects include: Headache Dry mouth Stomach problems like nausea, stomach pain, or constipation Appetite and weight loss Agitation Anxiety Tinnitus (ringing in the ears) Dizziness Muscle pain Heart palpitations Trouble sleeping Blurred vision In some cases, serious side effects may occur, such as seizures or high blood pressure

Age, injury severity, concurrent therapies, and individual biochemistry all influence outcomes

This controlled release offers several advantages: It improve the stability of antioxidants by preventing their degradation in circulation [17]