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12 In acute ICD, studies using both human and animal models show that acute damage to the epidermal barrier (such as that caused by sodium lauryl sulfate, a surfactant used in many cleaning and hygiene products) triggers the release of preformed cytokines from keratinocytes, including interleukin (IL)-1, IL-1, IL-6, and tumor necrosis factor (TNF)-

The micro is there because the skin still looks and feels normal

skin, recovery, growth hormone release)

As of 2025, no GLP-1 based therapy has been shown to definitely modify the disease

For others, Evers said the drugs can be a key stepping stone to get approval for or prepare for bariatric surgery when their initial body mass index (BMI) puts them outside surgical safety parameters

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